Serenin Vet<sup>®</sup> (45ct)
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Serenin Vet<sup>®</sup> (45ct) thumbnail

Serenin Vet® (45ct)

Serenin Vet® combines different ingredients that work together to promote normal behavioral patterns and a healthy nervous system, particularly in times of stress.
Click thumbnails to learn more about each ingredient:
St. John's Wort
St. John's Wort
St. John’s Wort (Hypericum perforatum), a plant that grows in the wild, helps support normal behavioral patterns and maintains proper functioning of the nervous system. The flowers and leaves of St. John's Wort contain active ingredients such as hyperforin.
St. John's Wort
Inositol
Inositol
Inositol is a carbohydrate found in your body, as well as in food and dietary supplements. It is used to support metabolic functioning of the liver as well as help maintain normal emotional balance. Inositol also acts as an antioxidant to help remove damaging free radicals in the brain, circulatory system, and other body tissues.
Inositol
Eleuthero powder
Eleuthero powder
Eleuthero powder is an adaptogen that aids in the body’s ability to cope with environmental stress and anxiety by modulating the nitric oxide and cortisol production via the hypothalamic-pituitary axis.
Eleuthero powder
Passion Flower Extract
Passion Flower Extract
Passion flower extract is a key ingredient containing flavonoids and alkaloids, promoting relaxation by inhibiting GABA uptake by nerve cell synapses.
Passion Flower Extract
$40.00
Buy 2 for $36.00 each
Buy 3 for $34.00 each
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45 Capsules per Bottle     //     Product Code: AN214-45     //     Price For US Customers Only.
  • General Info
  • For Veterinarians
  • Directions for Use
  • Ingredients

Serenin Vet® combines different ingredients that work together to promote normal behavioral patterns and a healthy nervous system, particularly in times of stress. These ingredients work together to achieve this calming effect and include:

  • St. John’s Wort extract, to promote normal behavioral patterns and functioning of the brain and nervous system.
  • Eleuthero powder, to support behavioral responses to stress.
  • Passion flower extract, which promotes relaxation.
  • DL-phenylalanine, an essential amino acid that promotes normal behavior and attention and balances temperament.
  • 5-HTP (Griffonia simplicifolia seed), from an African evergreen climbing shrub, promotes calming behaviors by supporting a normal nervous system response to stress.

Special Note: If your animal is pregnant or actively breeding, or is receiving any medications for behavioral management, please contact Animal Necessity Veterinary Consultants or call us at 1-800-721-1310, or contact your veterinarian before using this supplement.

Serenin Vet® combines different ingredients that work together to promote normal behavioral patterns and a healthy nervous system, particularly in times of stress. These ingredients work together to achieve this calming effect and include:

  • St. John’s Wort extract, with active constituents hyperforin and hypericin, promotes healthy mentation and behavioral patterns by modulating serotonin, dopamine, and norepinephrine; reducing serotonin reuptake in the brain; and inhibiting GABA ligand binding.1
  • Eleuthero powder, an adaptogen, aids in the body’s ability to cope with environmental stress and anxiety by modulating the nitric oxide and cortisol production via the hypothalamic-pituitary axis.2
  • Passion flower extract, containing flavonoids and alkaloids, promotes relaxation by inhibiting GABA uptake by nerve cell synapses.3
  • DL-phenylalanine, an essential amino acid, promotes normal mood and behavior by maintaining healthy amounts of norepinephrine, as it is a precursor for the neurotransmitter’s production. DL-phenylalanine’s conversion to the neuromodulator 2-phenylethylamine also helps encourage brain neuron receptor sensitivity4.
  • 5-HTP (Griffonia simplicifolia seed), a metabolite produced from the essential amino acid L-tryptophan and a direct precursor for serotonin production in the CNS that promotes serotonin production and thereby healthy behavioral responses in times of stress.5

Special Considerations: Not recommended for use in pregnant or actively breeding without veterinary consultation. Also not recommended for use if patient is receiving any other behavior modification medications, like MAOI’s. Recommend to give with food to reduce change of gastrointestinal upset. If any questions, please contact Animal Necessity Veterinary Consultants or call us at 1-800-721-1310, or contact your veterinarian before using this supplement.


References

1 Butterweck V, Wall A, Lieflander-Wulf U, Winterhoff H, and Nahrstedt A. Effects of the total extract and fractions of Hypericum perforatum in animal assays for antidepressant activity. Pharmacopsychiatry. 1997; 30(Suppl 2): 117-124.

2 Wilson L. Review of adaptogenic mechanisms: Eleuthrococcus senticosus, Panax ginseng, Rhodiola rosea, Schisandra chinensis, and Withania somnifera. Australian Journal of Medical Herbalism. 2007; 19(3): 126-131.

3 Appel K, Rose T, Fiebich B, Kammler T, Hoffman C, and Weiss G. Modulation of the γ-aminobutyric acid (GABA) system by Passifora incarnata L. Phytother Res. 2011; 25(6): 838-843.

4 Kravitz HM, Sabelli HC, and Fawcett J. Dietary supplements of phenylalanine and other amino acid precursors of brain neuroamines in the treatment of depressive disorders. J Am Osteopath Assoc. 1984; 84(1 Suppl): 119-123.

5 Birdsall TC. 5-Hydroxytryptophan: A clinically effective serotonin precursor. Altern Med Rev. 1998; 3: 271-280.

Weight (lbs.) Daily Use
1-4 Contact Us for Dosage Guidelines
5-15 1/2 Capsule
16-50 1 Capsule
51-100 1 Capsule A.M. and 1/2 Capsule P.M.
101-200 1 Capsule A.M. and 1 Capsule P.M.
201-300 2 Capsules A.M. and 1 Capsule P.M.
301-500 2 Capsules A.M. and 2 Capsules P.M.
501-700 3 Capsules A.M. and 2 Capsules P.M.
701-900 3 Capsules A.M. and 3 Capsules P.M.
901-1200 4 Capsules A.M. and 3 Capsules P.M.
1201-1500 4 Capsules A.M. and 4 Capsules P.M.
1501+ Contact Us for Dosage Guidelines
Serving Size: 1 Capsule
//
Capsules Per Bottle: 45
Active Ingredients Amount Per Serving
St. John's Wort Extract (Hypericum perforatum)
(Flower Heads) standardized for 0.3% Hypericin 1.8mg
300 mg
Inositol 50 mg
Magnesium (Magnesium Oxide) 50 mg
Eleuthero Powder (Eleutherococcus senticosus) (Rhizome) 35 mg
Passion Flower Extract (Passiflora incamata) (Aerial Parts) standardized for > 3.5% flavonoids as Isovitexin 1.75 mg 25 mg
DL-Phenylalanine 25 mg
5-HTP L-5-hydroxy-tryptophan (Griffonia simplicifolia) (Seed) 12.5 mg
Vitamin B-6 (Pyridoxine HCI) 12.5 mg
L-Tyrosine 5 mg
Folate (Folic Acid) 200 mcg
Vitamin B-12 (Cyanocobalamin) 100 mcg
Selenium (Selenium Amino Acid Chelate) 35 mcg
Inactive Ingredients: Inactive Ingredients: Rice flour, gelatin, magnesium stearate, silica
Extra Information:
Cautions: Safe use in pregnant animals or animals intended for breeding has not been proven. Do not use Serenin Vet™ if animal is on a Monoamine Oxidase Inhibitor (MAOI) or other type of antidepressant. Administer during or after the animal has eaten to reduce the incidence of gastrointestinal upset.

Special Note: St. John’s wort in Serenin Vet® is metabolized by the Cytochrome P450 liver pathway similar to CBD. Therefore, if taking both supplements, contact ANVision Necessity®.