Ocu-GLO<sup>®</sup> XL Chewables (30 Ct)
Ocu-GLO<sup>®</sup> XL Chewables (30 Ct) thumbnail
Ocu-GLO<sup>®</sup> XL Chewables (30 Ct) thumbnail
Ocu-GLO<sup>®</sup> XL Chewables (30 Ct) thumbnail

Ocu-GLO® XL Chewables (30 Ct)

Ocu-GLO is the #1 Veterinarian Recommended Eye Health Supplement by Veterinary
Ophthalmologists Around the World!Ocu-GLO is the #1 Veterinarian Recommended Eye Health Supplement by Veterinary Ophthalmologists Around the World!
Ocu-GLO® XL Chewables for Medium to Large Dogs are a blend of different antioxidants that complement traditional therapy for eye health. This supplement is formulated to protect vital cells in the eye against free radical damage, to support normal cellular health and function. Ocu-GLO® XL Chewables include Grape seed extract, Lutein and Omega-3 fatty acids, and also Astaxanthin and Rutin for enhanced antioxidant support! Our XL Chewables are a great choice for dogs with sensitive GI tracts. Ocu-GLO® XL Chewables are safe for perioperative use, and are tasty supplements that are easy to administer!
Click thumbnails to learn more about each ingredient:
Grape Seed Extract
Grape Seed Extract
Grape seed extract, which is made from the seeds of wine grapes, is rich in antioxidants and helps maintain a normal inflammatory response. Grape seed extract contains proanthocyanidins, which have been studied for a variety of health conditions.
Grape Seed Extract
Lutein is a rich source of carotenoid antioxidants necessary for protection against free radical damage in the retina and lens.
Omega-3 Fatty Acids
Omega-3 Fatty Acids
Omega-3 fatty acids contains essential fatty acids that support retinal health and cannot be synthesized in the body (the body cannot make on its own). They are an essential fat, which means they are needed to survive.
Omega-3 Fatty Acids
Vitamin C
Vitamin C
Vitamin C, also known as ascorbic acid, is a potent water-soluble antioxidant that is necessary for the growth, development, and repair of all body tissues. Vitamin C is vital to your body's healing process.
Vitamin C
Vitamin E
Vitamin E
Vitamin E is found naturally in some foods, added to others, and available as a dietary supplement. Vitamin E is the collective name for a group of fat-soluble compounds that provide antioxidant support.
Vitamin E
Green Tea Leaf Extract
Green Tea Leaf Extract
Green tea extract is its concentrated form, with just one capsule containing the same amount of active ingredients as an average cup of green tea. Like Green tea, Green tea extract is a great source of antioxidants. These have been credited with a range of health benefits.
Green Tea Leaf Extract
Alpha Lipoic Acid
Alpha Lipoic Acid
Alpha Lipoic Acid, or ALA, is an occurring antioxidant that's made in the body. Alpha Lipoic Acid is a universal antioxidant that is important for normal liver function and vision.
Alpha Lipoic Acid
Aids in blood circulation and helps your body produce collagen. Rutin enhances vitamin C activity to scavenge free radicals but can also possess some of this activity on its own.
Astaxanthin helps to filter harmful blue light from the eyes and improve blood flow.
Buy 2 for $54.00 each
Buy 3 for $51.00 each
Check back soon for product availability! All of our specialty animal health products are produced in small batches. Small batch production ensures the highest quality, freshness and effectiveness of our products for our customers.

   Please call 1-800-721-1310 for more information on how to order!

30 Chewables per Jar     //     Product Code: ANRX16     //     Price For US Customers Only.
  • General Info
  • For Veterinarians
  • Directions for Use
  • Ingredients

How does Ocu-GLO® XL Chewables differ from Ocu-GLO® Gel-Caps or Ocu-GLO® Powder Blend?

  • Formed into a convenient chew!
  • Easier administration at mealtime for medium to large dogs
  • Optimal for pets with sensitive GI tracts
  • They are soy-free and contain a palatable artificial chicken-flavor for pets allergic to chicken or soy
  • Formulated by board-certified veterinary ophthalmologists
  • Includes GLO® for optimal vision health: Grape seed extract, Lutein and Omega-3 fatty acids
  • Specifically formulated to support canine eyes
  • Astaxanthin, Green Tea Extract, and Rutin for enhanced antioxidant support

Have a question about Ocu-GLO®? Please visit our Frequently Asked Questions and the Ocu-GLO® official website!

Store this product in a cool, dry place (59 - 86 degrees Fahrenheit / 15 - 30 degrees Celsius).
Ocu-GLO® is formulated with different antioxidants that work to support eye health through the quenching of reactive oxygen species (ROS). These active ingredients include:
  • GLO® Proprietary Blend
    • Grape seed extract: Grape seed extract contains different proanthocyanidins such as: catechin, epicatechin and gallic acid, which work to inhibit key components of reactive oxygen species production and stress induced cell signaling in the canine lens epithelium.1
    • Lutein: Lutein is a carotenoid that has a large body of evidence that supports its antioxidant activity in the eye. Lutein deficiency has been associated with an increased risk of age-related macular degeneration.2 Lutein supplementation also increases lymphocyte proliferative response and the expression of major hiscompatability complex II (MHC II).3
    • Omega-3 fatty acids: Omega-3 fatty acids, in the form of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), regulate the inflammatory response, vascular death and regeneration, and photoreceptor apoptosis (cell death) in the eye. A decrease in DHA has been associated with an increase in cytokine-induced proinflammatory signaling in the retina. An increase in both EPA and DHA have been shown to reduce blood vessel damage and hypoxic injury after a retinal insult, as well as reduce photoreceptor apoptosis.4
  • Vitamin C: Vitamin C, in the form of ascorbic acid, is a water soluble vitamin and antioxidant that is vital to the healing process. It is required for neutrophil apoptosis and clearance, and contributes towards collagen synthesis, maturation, secretion, and degradation.5
  • Green tea leaf extract: Green tea leaf extract is a great source of antioxidants that have been credited with a range of health benefits. Green tea leaf extract contains catechins that have been shown to regulate the inflammatory response in the eye from infectious, non infectious, and oxidative complications.6
  • Vitamin E: Vitamin E refers to a group of fat-soluble compounds. Supplementation of one of these compounds, α-tocopherol, attacks free radicals to prevent lipid oxidation in retina and other body tissues.7,8
  • Alpha Lipoic Acid: Alpha Lipoic Acid, or ALA, is an essential cofactor for the synthesis of glutathione, the body’s most potent endogenous antioxidant. ALA and glutathione both work to scavenge free radicals to protect the lens from oxidative stress.9
  • Coenzyme Q10: Coenzyme Q10, or CoQ-10, is a naturally occurring quinone found in most organisms. CoQ-10 is essential for the health of virtually all tissues since it is involved with the production of adenosine triphosphate (ATP). Decreases in CoQ-10 have been linked to the development diseases that result in an increase in reactive oxygen species (ROS), as its antioxidant activity helps prevent modifications of proteins and DNA by ROS.10
  • Zinc: Zinc is a mineral that has potent antioxidant activity. Zinc can help protect membranes from iron-initiated lipid oxidation while working synergistically with other antioxidants.11
  • Vitamin B1 (Thiamin HCl): Vitamin B1 is important for neuromuscular development and aids in cellular metabolism.
  • Vitamin B3 (Niacin): Vitamin B3 may help lower serum triglyceride, cholesterol, low density lipoprotein, and very low density lipoprotein levels in the blood.
  • Vitamin B5 (d-calcium Pantothenate): Vitamin B5 is essential for the breakdown of fatty acids, amino acids, steroids, and cholesterol. Vitamin B5 also functions as an antioxidant.
  • Vitamin B6 (Pyridoxine HCl): Vitamin B6 helps with hemoglobin formation as well as the metabolism of fats, carbohydrates, and proteins.
  • Vitamin B7 (Biotin): Biotin is an enzyme cofactor involved in the metabolism of amino acids and the biosynthesis of fats and carbohydrates.
  • Vitamin B9 (Folic Acid): Vitamin B9 is important for cell growth and development.
  • Vitamin B12 (Cyanocobalamin): Vitamin B12 is an enzyme cofactor that is essential for cell growth and red blood cell development.
  • Taurine: Taurine is essential in cats for them to properly absorb nutrients, meaning that they cannot make it on their own and must get it through their diet. Taurine can also do the same in dogs, it just is not essential in their diet.
  • Rutin: Rutin can inhibit the release of reactive oxygen species and increase the release oxidative stress factors, such as glutathione and superoxide dismutase.12
  • Astaxanthin: Astaxanthin is a potent free radical scavenger that inhibits blue light induced cell apoptosis and diminished mitochondrial damage.13


1. Barden CA, Chandler HL, Lu P, Bomser JA, Colitz CMH. 2008. Effect of grape polyphenols on oxidative stress in canine lens epithelial cells. Am J Vet Res 69(1):94-100.

2. Bernstein PS, Zhao DY, Wintch SW, Ermakov IV, McClane RW, Gellermann W. 2002. Resonance raman measurement of macular carotenoids in normal subjects and in age-related macular degeneration patients. Ophthalmology 109(10):1780-1787.

3. Kim HW, Chew BP, Wong TS, Park JS, Weng BB, Byrne KM, Hayek MG, Reinhart GA. 2000. Dietary lutein stimulates immune response in the canine. Vet Immunol Immunopathol 74(3-4):315-327.

4. Querques G, Forte R, Souied ER. 2011. Retina and omega-3. J Nutr Metab 2011:748361.

5. Moores J. 2013. Vitamin C: a wound healing perspective. Br J Community Nurs: S8-S11.

6. Li J, Du L, He JN, Chu KO, Guo CL, Wong MOM, Pang CP, Chu WK. 2021. Anti-inflammatory effects of GTE in eye diseases. Front Nutr 8:753955.

7. Mejia-Fava J, Colitz CMH. 2014. Supplements for exotic pets. Vet Clin Exot Anim 17:503-525.

8. Rasmussen HM, Johnson EJ. 2013. Nutrients for the aging eye. Clin Interv Aging 8:741-748.

9. Mandelker L, Wynn S. 2004. Cellular effects of common nutraceuticals and natural food substances. Vet Clin Small Anim 34: 339-353.

10. Saini R. 2011. Coenzyme Q10: the essential nutrient. J Pharm Bioallied Sci 3(3):466-467.

11. Zago MP, Oteiza PI. 2001. The antioxidant properties of zinc: interactions with iron and antioxidants. Free Radic Biol Med 31(2):266-274.

12. Zhao B, Zhang W, Xiong Y, Zhang Y, Zhang D, Xu X. 2020. Effects of rutin on the oxidative stress, proliferation and osteogenic differentiation of periodontal ligament stem cells in LPS-induced inflammatory environment and the underlying mechanism. J Mol Histol 51(2):161-171.

13. Lin CW, Yang CM, Yang CH. 2020. Protective Effect of Astaxanthin on Blue Light Light-Emitting Diode-Induced Retinal Cell Damage via Free Radical Scavenging and Activation of PI3K/Akt/Nrf2 Pathway in 661W Cell Model. Mar Drugs 18(8):387.

Weight (lbs.) Daily Use
1 - 10 Use 1/2 XL Chew

You can also use Ocu-GLO® Chewables (60 Ct) for Small Dogs and Cats.
11-30 1 XL Chew
31-60 2 XL Chews
61+ 3 XL Chews

If daily suggested use is more than one soft chew, divide up to give during multiple meals. Store in a cool dry place.

WARNINGS: Not for human consumption. Keep out of the reach of children and animals. In case of accidental overdose, contact a health professional immediately.

Serving Size: 1 Chewable
Chewables Per Jar: 30
Active Ingredients Amount Per Serving
Taurine 500 mg
GLO® Proprietary Blend of (Omega 3 EPA/DHA, Grape Seed Extract, Lutein) 351 mg
Vitamin C (Ascorbic Acid) 100 mg
Vitamin E (D-alpha Tocopheryl Acetate) 50 IU
Green Tea Leaf Extract 40 mg
Alpha Lipoic Acid 26 mg
Co-Q10 (Ubiquinone) 26 mg
Rutin 10 mg
Zinc (Zinc Oxide) 6 mg
Niacinamide 2.4 mg
Astaxanthin 2 mg
Pantothenic Acid (Calcium-D-pantothenate) 2 mg
Vitamin B-2 (Riboflavin) 1 mg
Vitamin B-1 (Thiamine Mononitrate) 0.2 mg
Vitamin B-6 (Pyridoxine HCI) 0.2 mg
Folic Acid 40 mcg
Biotin 20 mcg
Vitamin B-12 (Cyanocobalamin) 5 mcg
Inactive Ingredients: Arabic gum, brewer's yeast, citrus pectin, fish oil, glycerin, imitation chicken flavor, mixed tocopherols, oat flour, oat meal, propionic acid, rosemary extract, sorbic acid, sunflower lecithin, sunflower oil, water.
Extra Information:
Cautions: If animal's condition worsens or does not improve, stop product administration and consult your veterinarian. Safe use in pregnant animals or animals intended for breeding has not been proven. Administer during meals or after the animal has eaten to reduce incidence of gastrointestinal upset. Discontinue if gastrointestinal upset persists, and contact your veterinarian. Do not use with anticoagulants; please call 1-800-721-1310 with any questions/concerns.

GLO® is a trademark of Animal Health Quest Solutions; Patent US8709515